Call 1-800-355-6000 to order. NV Perricone is also available at select bluemercury store locations including Rittenhouse Square, Suburban Square, Princeton, Marlton Square, Shrewsbury and Hinsdale. After years of research Dr. Perricone arrived at the conclusion that cellular inflammation may be the underlying cause of wrinkles. According to Dr. Perricone, this inflammation is not the redness that is visible to the naked eye but rather microscopic irritation that takes place in your cells leading to cellular damage. He believes that this inflammation is responsible for skin-related problems like breakouts, wrinkles, and loss of firmness. Dr. Perricone's holistic approach to aging treats this inflammation in three ways: through diet, nutriceutical supplements, and his award-winning line of skin care products and cosmeceuticals.